A man with a fatal medical condition has spoken exclusively to MailOnline about how he is set to become the first person to undergo a head transplant and hopes it could be as soon as next year.
Valery Spiridonov says he is ready to put his trust in controversial surgeon Dr Sergio Canavero who claims he can cut off his head and attach it to a healthy body.
Mr Spiridonov, 30, a computer scientist from Russia, said: 'My decision is final and I do not plan to change my mind.'
As a lifelong sufferer of the rare genetic Werdnig-Hoffman muscle wasting disease, he says he wants the chance of a new body before he dies.
'Am I afraid? Yes, of course I am. But it is not just very scary, but also very interesting,' said Mr Spiridonov from his home in Vladimir, a city 120 miles east of Moscow.
'But you have to understand that I don't really have many choices', he said. 'If I don't try this chance my fate will be very sad. With every year my state is getting worse.'
Dr Canavero and Mr Spiridonov have talked via Skype though they have not met yet and the doctor has not reviewed his medical records.
The Italian told CNN he has received many email and letters from people seeking the procedure but he insists the first patients will be people suffering from a muscle wasting disease.
Dr Canavero has named the procedure HEAVEN, which is an acronym for head anastomosis venture. Anastomosis involves the surgical connecting of two parts. He insists all the necessary techniques already exist to transplant a head onto a donor body.
Controversial: Surgeon Dr Sergio Canavero |
The first monkey head transplant was performed 45 years ago and a basic operation on a mouse was carried out in China recently.
But critics say Dr Canavero's plans are 'pure fantasy'. The Italian has been compared to the fictional gothic-horror character Dr Frankenstein.
And Arthur Caplan, the director of medical ethics at New York University's Langone Medical Centre, has described Dr Canavero as 'nuts'.
Dr Hunt Batjer, president elect of the American Association for Neurological Surgeons, told CNN: 'I would not wish this on anyone. I would not allow anyone to do it to me as there are a lot of things worse than death.'
The cost of the 36-hour operation, which could only be performed in the one of the world's most advanced operating theatres, has been estimated at £7.5million.
The new body would come from a transplant donor who is brain dead but otherwise healthy.
Both donor and patient would have their head severed from their spinal cord at the same time, using an ultra-sharp blade to give a clean cut.
The patient's head would then be placed onto the donor's body and attached using what Canavero calls his 'magic ingredient' - a glue-like substance called polyethylene glycol - to fuse the two ends of the spinal cord together.
The muscles and blood supply would be stitched up, before the patient is put into a coma for four weeks to stop them from moving while the head and body heal together.
When they wake the patient should be able to move, feel their face and even speak with the same voice. Powerful immunosuppressant drugs should stop the new body from being rejected.
Critics say Dr Canavero has simplified the difficulties involved in reattaching a spinal cord. The Italian doctor has also so far failed to secure funding for the staff of 150 doctors and nurses he believes are required to complete the procedure.
However, the Italian is confident he can successfully transplant a head on to another body.
And if successful, his pioneering procedure could give new hope to thousands of paralysed and disabled people.
Mr Spiridonov was diagnosed with the rare muscle-wasting condition, Werdnig-Hoffman disease, at the age of one. Tragically the disease progresses every day.
He told MailOnline: 'I can hardly control my body now. I need help every day, every minute. I am now 30 years old, although people rarely live to more than 20 with this disease.'
He continued: 'My muscles stopped any development in childhood. Because of this, they do not grow and the skeleton gets deformed. The back muscles cannot support the skeleton.'
With his condition worsening each day, Mr Spiridonov is desperate for the technique to work. He told MailOnline: 'If you want something to be done, you need to participate in it.
'I do understand the risks of such surgery. They are multiple. We can't even imagine what exactly can go wrong. I'm afraid that I wouldn't live long enough to see it happen to someone else.'
He said his family fully support his decision to be the first human to undergo such surgery.
Mr Spiridonov added: 'What's more, there's already a lot of effort invested in this idea and that's why it's too late to back out.
'I came up with this idea quite some time ago. I read many scientific articles on this topic
Mr Spiridonov denies his pledge to be a guinea pig is a stunt, and insists he goes into it with his eyes open.
'If I want this kind of surgery to happen, I shouldn't put the responsibility onto someone else but should try it on myself.
'My family fully supports me. They also understand all the risks and even if they think that it's too dangerous, they still support me in my decision.'
Despite his severe disabilities Mr Spiridonov has led a full life, graduating from university with a degree in computer science.
He added: 'I don't do this because I don't have a life but I think that science is developed by those who are ready to take risks and devote themselves to it.'
Mr Spiridonov has never discussed the possibility of failure with Dr Canavero.
He told MailOnline: 'It was about me just offering myself as ready to undergo it. Of course, the professor considers the chances to succeed are quite high otherwise he wouldn't try it.'
He says there is no ethical difference between transplanting a head on to a healthy body and replacing a damaged organ with a healthy one, which is now considered routine.
Donors could include victims of road traffic accidents or even prisoners sentenced to death, he says.
He told MailOnline: 'I consider it to be as ethical as the transplant of the heart or kidneys. At some point of time this was considered to be unethical as well.
'There was much talk about where the human soul is located, and if it's ethical to do the heart transplants, but now doctors do it and save people's lives.
'I think it's the normal way of technology to evolve. It would be strange to stop at this point when the neurosurgery is ready to take the next step.
'The bodies used for transplant could be those of people whose brain was damaged, let's say in a car crash or motorbike accident, or who are sentenced to capital punishment.
'But, of course, in future humanity should learn how to grow healthy bodies for the transplants so there will be no shortage of organs and bodies.'
Mr Spiridonov says he understands that the Italian surgeon can only go ahead when he is satisfied that medical science is sufficiently advanced.
But the Russian he believes this moment is very close, possibly next year, 2016.
He told MailOnline: 'We haven't agreed on a particular date of the surgery with Dr Canavero
'It's an ongoing process and a lot depends on the success of the studies that are underway now.
'There will be a conference of neurosurgery in Annapolis in the US this summer. The professor will be reporting on his studies there.
'He would like me to be present. I would like to attend if I can find the means to fly there. We will see what the next step is after that.'
Matter-of-factly, he adds: 'For now we are thinking about transplanting my head in 2016.'
The Russian even jokes about what might happen if the surgery goes wrong.
He told MailOnline: 'Maybe I would try to move my leg but instead my body will produce a litre of adrenaline. But I am willing to take the risks and try.'
In 1970 Dr Robert White transplanted the head of one monkey onto the body of another at the Case Western Reserve University School of Medicine.
The monkey died after eight days because the body rejected the head. The monkey was unable to breathe on its own. The animal could not move because the spinal cord were not connected.
Dr Batjer says White's research does not provide evidence that a human head transplant can work.
He told CNN: 'It's a 45-year-old reference in a primate and there is no evidence that the spinal cord was anastomosed functionally.'
Dr Sergio Canavero could not be reached for comment. ....culled
Wow!
ReplyDeleteMbiachi Chineke di nso!
ReplyDeleteAll the best o
DeleteAnything is possible but definitely not this one. It's just mere fantasy.
ReplyDeleteGOD BLESS NIGERIA.
Sounds nuts to me. But the patient really doesn't have a choice. What's he got to loose anyway? O di egwu
ReplyDeleteHis head!
DeleteNo pun? intended
I read about it on daily mail. Poor guy... He feels he's living on borrowed time anyway & that he has nothing to lose doing the operation. If this goes well it will change a LOT of things in this world
ReplyDeleteCan't work abeg! All the nerves that send signals to d brain how dem wan take join em together?
ReplyDeleteOh well kudos to the man for volunteering and to the doctor for trying, cos na so e dey start, d next doctor crazy enough to try it will improve on d mistakes this one made. One day...it may be possible
Its very possible, the human mind is very complex. Though would prefer it is carried out and perfected on a primate before being tried out on human. I pray they succeed.
DeleteUh??
ReplyDeleteI will like to be among the nurses during the surgery such sight put me a good mood and for his sake I hope it works or else he (doctor)will find himself in a psychiatrists and his licence lost
ReplyDeleteDont try God ooo. i know scientist are working. i like your optimistic but dont try God.
ReplyDeletena my advice be dat for you
Does that Doctor know God??
DeleteI doubt.
I dont ve much to say, just waiting.... until it happen
ReplyDeleteWonders shall never end,as the monkey and rabbit head transplant worked out succesfully,so human head transplant will work out?? Okay na
ReplyDeleteHmmm I fear for the man. If he want's to die let him do that peacefully na instead of passing through pains before dying?
ReplyDeleteHaaaa.
ReplyDeleteBut can this ever be practically possible???
I doubt dou
Na wao. God is truly wonderful. May his name be praised now and for ever
ReplyDeleteSay what?????
ReplyDeleteI really like the fact that these guy like pushing to know more and expand what science can do, but this...... I don't know mehn.
ReplyDeleteThis is wired? What happens to the heart and entire body will it accept a totaly strange body? .
ReplyDeleteNa wa o!
ReplyDeleteThis shii is scary!
I hope the man doesn't go thru with it.
Then again, if it does work.....
This sounds really cool but highly risky!
ReplyDeleteI Hope it works out.
Let me memorize his name so that when I hear that he couldn't make it, I wouldnt HV to think hard to know it was his story, this same story. Tufiakwa
ReplyDeletethey want to use his head for experiment,hmmmmmmmmm
ReplyDeleteWait..if his head enters anoda body,will his spirit enter d new body too abi is d spirit in d brain?if dis works nd he's himself in d new body,will dat mean dat wen don't av a soul?
ReplyDeleteWaoh! I kinda feel funny with this. A whole human head? Hain! There are lots of 'what if's' so many questions but very few answers. Hmmmmm
ReplyDeleteWhat won't we read and hear inthis world? Can't wait to read about it by next year.
ReplyDeleteCan the head survive on a separate body ?
ReplyDeleteOk let's wait and see.
And how will the spinal cord work?
ReplyDeleteThe immunosuopresants hve to be really powerful so as to prevent d host from rejecting d head.
ReplyDeleteScience....
ReplyDeleteWell until when I read about its success.
This is just opting for legal suicide. There is just no way this will work. If the Dr claims he knows what he is doing then I wish them all the best.
ReplyDeleteOh wow! Quite a risky venture
ReplyDeleteWow! The God that made us also gave brain to do some things.... Hmmmmm nothing is impossible but this one??? E go hard o. God dey.
ReplyDeleteWhat??!!
ReplyDeleteHumph!
....but the head controls everything...how possible?
Nitty.
LMAO is just all I can do....after this Una go respect God
ReplyDelete